(2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid
N-phthaloyl-L-phenylalanine
CAS: 5123-55-7
Molecular Formula: C17H13NO4
(2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid - Names and Identifiers
| Name | N-phthaloyl-L-phenylalanine |
| Synonyms | PHT-PHE-OH N-Phthaloyl-Phe-OH PHTHALYL-L-PHENYLALANINE N-Phthaloyl-Phenylalanine PHTHALOYL-L-PHENYLALANINE N-PHTALOYL-L-PHENYLALANINE N-phthaloyl-L-phenylalanine N-PHTHALOYL-L-PHENYLALANINE N-PHTHALOYL-L-PHENYLALANINE extrapure (2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid (2S)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-phenylpropanoic acid |
| CAS | 5123-55-7 |
| InChI | InChI=1/C17H13NO4/c19-15-12-8-4-5-9-13(12)16(20)18(15)14(17(21)22)10-11-6-2-1-3-7-11/h1-9,14H,10H2,(H,21,22)/t14-/m0/s1 |
(2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid - Physico-chemical Properties
| Molecular Formula | C17H13NO4 |
| Molar Mass | 295.29 |
| Density | 1.358 g/cm3 |
| Melting Point | 181-185°C |
| Boling Point | 498.0±38.0 °C(Predicted) |
| Flash Point | 255°C |
| Solubility | Soluble in methanol. (almost transparency) |
| Vapor Presure | 9.78E-11mmHg at 25°C |
| Appearance | Powder |
| Color | White |
| pKa | 3.50±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Hygroscopic |
| Refractive Index | -216.5 ° (C=2, EtOH) |
| MDL | MFCD00069738 |
(2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 3-10 |
| HS Code | 29242990 |
(2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-phenylpropanoic acid - Introduction
N-phthaloyl-L-phenylalanine is an organic compound whose chemical formula is C18H15NO4. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: N-phthaloyl-L-phenylalanine is a white crystalline solid.
-Solubility: It is almost insoluble in water, but can be dissolved in organic solvents, such as ethanol, methanol and chloroform.
-Melting point: The melting point of the N-phthaloyl-L-phenylalanine is about 142-144°C.
-Hydrolytic stability: It is relatively stable under acidic conditions.
Use:
N-phthaloyl-L-phenylalanine have many applications in chemistry and biochemistry:
-As an active site protector: It can be used as a substrate protector in enzyme-catalyzed reactions to protect the active site of the substrate.
-As an inducer: It can be used to synthesize chiral compounds, such as chiral drugs and synthetic materials.
-As an intermediate in organic synthesis: It can be used to synthesize compounds with specific structures and functions, such as polymers and materials.
Preparation Method:
The preparation of N-phthaloyl-L-phenylalanine is generally carried out by the following steps:
1. Using phthalic acid and L-phenylalanine as raw materials, ester exchange reaction was carried out under appropriate conditions to prepare N-phthaloyl-L-phenylalanine ester.
2. hydrolyze the N-phthaloyl-L-phenylalanine ester to obtain the N-phthaloyl-L-phenylalanine.
Safety Information:
- N-phthaloyl-L-phenylalanine security data is still limited and needs to be handled carefully.
-Care should be taken to wear appropriate protective equipment, such as laboratory gloves, masks, and goggles, when using or handling the compound.
-Avoid inhaling dust of the substance, contact with the skin, or getting into the eyes.
-When using the compound, it should be placed in a well-ventilated environment and avoid contact with strong acids and strong bases.
Please note that the properties, uses and safety information of this compound are for reference only, and specific use should be subject to relevant laboratory or professional guidance.
Nature:
-Appearance: N-phthaloyl-L-phenylalanine is a white crystalline solid.
-Solubility: It is almost insoluble in water, but can be dissolved in organic solvents, such as ethanol, methanol and chloroform.
-Melting point: The melting point of the N-phthaloyl-L-phenylalanine is about 142-144°C.
-Hydrolytic stability: It is relatively stable under acidic conditions.
Use:
N-phthaloyl-L-phenylalanine have many applications in chemistry and biochemistry:
-As an active site protector: It can be used as a substrate protector in enzyme-catalyzed reactions to protect the active site of the substrate.
-As an inducer: It can be used to synthesize chiral compounds, such as chiral drugs and synthetic materials.
-As an intermediate in organic synthesis: It can be used to synthesize compounds with specific structures and functions, such as polymers and materials.
Preparation Method:
The preparation of N-phthaloyl-L-phenylalanine is generally carried out by the following steps:
1. Using phthalic acid and L-phenylalanine as raw materials, ester exchange reaction was carried out under appropriate conditions to prepare N-phthaloyl-L-phenylalanine ester.
2. hydrolyze the N-phthaloyl-L-phenylalanine ester to obtain the N-phthaloyl-L-phenylalanine.
Safety Information:
- N-phthaloyl-L-phenylalanine security data is still limited and needs to be handled carefully.
-Care should be taken to wear appropriate protective equipment, such as laboratory gloves, masks, and goggles, when using or handling the compound.
-Avoid inhaling dust of the substance, contact with the skin, or getting into the eyes.
-When using the compound, it should be placed in a well-ventilated environment and avoid contact with strong acids and strong bases.
Please note that the properties, uses and safety information of this compound are for reference only, and specific use should be subject to relevant laboratory or professional guidance.
Last Update：2024-04-09 15:17:58
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CAS: 5123-55-7
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CAS: 5123-55-7
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